
NAD+ Nasal Spray
from $125/moon the 12-month plan
NAD+ is a substance your cells already use to turn food into energy and support normal repair work. Halwel offers it as a compounded prescription nasal spray. Human studies have not proven that nasal NAD+ improves energy, focus, recovery, or longevity, so care begins with a clear goal and a planned check-in—not a promised result.
Compare plan lengths
$149/mo × 12
$125/mo
$1,500 charged once your prescription is approved · you save $288
Check your eligibilityA licensed provider reviews every intake before treatment is prescribed.
FormulationNAD+ Nasal Spray 300mg/ml (15ml)
How NAD+ Nasal Spray works
We would rather you understand the medicine than take our word for it.
It helps cells transfer energy
NAD+ stands for nicotinamide adenine dinucleotide. It is a helper molecule cells use when turning food into usable energy. Your cells need it to work normally. That fact alone does not show that an NAD+ nasal spray provides a health benefit.
It helps with normal cell repair and signaling
Cells also use NAD+ during DNA repair, stress responses, and communication inside the cell. These jobs explain why researchers are interested in NAD+. They do not prove that this nasal spray will improve a symptom or prevent disease.
Covarrubias et al., Nature Reviews Molecular Cell Biology, 2021
Levels can change with age and illness
The way the body makes and uses NAD+ can change with age, illness, and the type of tissue. A blood level does not necessarily show what is happening in every organ or predict how someone will feel.
Thoughtful care in four clear steps

Medical intake
Tell us about your health history, current medications, goals, and prior treatment. This is a medical screening, not a product order.

Clinical review
A licensed clinician in your state independently decides whether treatment is appropriate. A prescription is not guaranteed.

Medication delivery
If prescribed, a licensed pharmacy prepares your medication and ships it in discreet packaging. Compounded medications are not FDA-approved.

Ongoing care
Use your portal for check-ins, dose questions, side effects, refills, and treatment changes. Your clinician can adjust or stop treatment based on your health and response.
What changes
The outcomes measured in trials, each with its source.
Essential to cellular energy
NAD⁺ is a coenzyme every cell uses to turn nutrients into usable energy (ATP) — it sits at the center of metabolism and cellular repair.
Rajman et al., Cell Metabolism 2018NAD⁺ declines as we age
Tissue NAD⁺ falls measurably with age across humans and other species — the well-documented change that is the rationale for restoring it.
Covarrubias et al., Nat Rev Mol Cell Biol 2021Fuels repair and resilience
NAD⁺ powers sirtuins and PARP enzymes — the cellular machinery behind DNA repair and the stress responses that keep cells healthy.
Verdin, Science 2015A measurable target
NAD⁺ therapy has one clear aim: raise NAD⁺. In human studies, NAD⁺ precursors increase blood NAD⁺ dose-dependently — a direct, measured effect on the molecule itself.
What to keep in mind: The strongest human pharmacokinetic data is for oral NAD⁺ precursors; response can vary by route, dose, and individual.
Trammell et al., Nat Commun 2016An active frontier of longevity science
NAD⁺ is among the most actively studied targets in aging biology, with human trials underway on energy, metabolic health, and healthy aging.
What to keep in mind: NAD⁺ therapy supports normal cellular biology; it is not a treatment or cure for any disease, and human outcome data is still emerging.
NAD+ Nasal Spray questions
What patients ask most before starting. If yours isn't here, your clinician answers it during review.
Halwel offers a one-month plan for compounded NAD+ nasal spray if a clinician prescribes it. NAD+ is a helper molecule cells use to turn food into energy and support normal repair work. Its role inside cells is well understood, but nasal NAD+ has not been proven to improve general wellness or longevity.
Limited. We know far more about what NAD+ does inside cells and about pills containing NAD+ building blocks than we know about spraying NAD+ into the nose. Results from a different substance or delivery method cannot be assumed to apply to this product.
No. This is a compounded prescription. FDA has not reviewed it for safety, effectiveness, or quality, and it is not a generic version of an FDA-approved NAD+ nasal product.
It is a trial for a set period of time. Before starting, you and the clinician choose a specific goal, record where things stand, set a review date, and agree on reasons to continue or stop. It is not a promise that treatment will work.
Choose one or two concrete measures before starting—for example, the frequency or severity of a defined symptom or the ability to complete a specific activity. A vague sense of “optimization” is difficult to evaluate and can encourage indefinite treatment without evidence.
Follow the pharmacy label and your clinician’s instructions. They tell you how many sprays to use, how often, how to prepare and store the bottle, and when it expires. Do not copy directions from another product.
Nasal irritation, burning, dryness, congestion, unpleasant taste, headache, or nausea may occur. Because the exact product has limited trial data, report unexpected symptoms rather than assuming they are normal.
Stop and seek guidance for a concerning reaction. The care plan should also stop or change if there is no meaningful benefit by the agreed review date. It should change if safe use becomes difficult or a new health issue affects the decision.
The one-month plan includes one 15 mL bottle of compounded NAD+ nasal spray, with 300 mg of NAD+ in each milliliter, if prescribed. It also includes clinician review, follow-up support, and shipping. There is no separate membership fee. Your total charge and renewal timing are shown before you commit.
When you’re ready, begin with a short medical intake.
A licensed clinician will review your health and decide whether treatment is appropriate.


